MicroRNA-21 Down-regulates Rb1 Expression by Targeting PDCD4 in Retinoblastoma
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منابع مشابه
MicroRNA-21 Down-regulates Rb1 Expression by Targeting PDCD4 in Retinoblastoma
Retinoblastoma (RB) is a children's ocular cancer caused by mutated retinoblastoma 1 (Rb1) gene on both alleles. Rb1 and other related genes could be regulated by microRNAs (miRNA) via complementarily pairing with their target sites. MicroRNA-21 (miR-21) possesses the oncogenic potential to target several tumor suppressor genes, including PDCD4, and regulates tumor progression and metastasis. H...
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ژورنال
عنوان ژورنال: Journal of Cancer
سال: 2014
ISSN: 1837-9664
DOI: 10.7150/jca.10456